Magnitude and Pattern of Hepatitis B Carriers in the General Population at a Tertiary Care Hospital.

  • Dr Giridhara Upadhyaya P M
  • Dr Supriya Christopher
  • Ramya Jayasimha Kempegowda Institute of Medical Sciences
Keywords: HBsAg, HBeAg, Anti-HBeAg, Hepatitis B virus, HBV


Hepatitis B virus (HBV) is a parenterally transmitted virus that has assumed great clinical significance of late. The clinical presentation of HBV ranges from asymptomatic or unapparent infection to acute liver failure. The estimation of the number of carriers in most studies is mostly done by the detection of the HBsAg in individuals, but the detection of the presence of the HBeAg and anti-HBe has not yet gained mainstream attention. This study was conducted to find the Hepatitis B carrier rate at a tertiary care hospital in Bangalore. The samples collected were tested for HBsAg using chemiluminescence assay and positive samples were further tested for HBeAg using radioimmunoassay. Samples were then classified and analyzed statistically. It was seen that 1.41% of individuals are carriers of HBsAg and among them, 6.89% are positive for HBeAg.