Occurrence of congenital tropical theileriosis associated with oxidative stress and antioxidant response in crossbreed newborn calves in New Valley Governor ate. Egypt.

  • Professor Dr.Fathy Ahmad osman Animal health research institute
Keywords: Congenital theileriosis, newborn calves, oxidative stress.

Abstract

     In this study the occurrence of intrauterine transmission pathway of theileria spp from infected cows to its offspring was evaluated and the oxidative stress of theileria infection on new born calves and its body reaction by antioxidant response was determined. Twenty pregnant cows at the last trimester stage of pregnancy and its offspring from some localities in New-Valley Governorate and suffering from theileriosis(different degree of parasitemia) by clinically and laboratory (blood smears and PCR test) examine .Examination of 18 living new born calves where the rest number of newborn calves(two calves) dead during parturition, revealed 7(38.88%) calves only were positive by direct smear and indicated massive parasitemia but by PCR test revealed 14 out of 18(77.77%) new born calves were positive. The mean value of hematological parameters indicated significant decrease in TRBCs count, HB content, PCV (%), MCV (f l), MCH (p g/dl) and MCHC (g/dl) and significant increase in TWBCs count in comparison to control healthy calves, while evaluation of oxidative stress which revealed significantly increased in both parameters (MDA and PCs) by (P < 0.001), and no significant change in catalyze enzyme and significant decrease in glutathione enzyme in comparison to healthy control group. Thereby from the results we can see the neonate calf acquired theileria annulata infection from her infected and/or immune carrier mother during gestation period and affected newborn calves develop clinical signs either soon after birth or during neonate life, lipid peroxidation is one of the important consequences of oxidative stress.

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References

1-Radostits, O.M., Blood, D.C. and Gay, C.C ; Veterinary Medicine- A text book of the diseases of Cattle, Sheep, Pigs, Goats and Horses(1994); 8th edn. Bailliere Tindall, London, U.K. pp 1210-1212.
2-Aiello, S.E. and Mays, A(1998); The Merck Veterinary Manual. 8 th ed th. Merck & Co Inc. New. Jursey, USA. 1998. pp 31-33.
3-Nazifi, S., Razavi, S.M., Esmailnejad , Z., Gheisari, H(2009); Study on acute phase proteins ( haptoglobin , serum amyloid A, fibrinogen, and ceruloplasmin) changes and their diagnostic values in bovine tropical theileriosis. Parasitol.J. Res. 2009. 105: 41-46.
4-Branco, S., Orvalho, J., Leitão, A., Pereira, I., Malta, M., Mariano, I., Carvalho, T., Baptista, R., Shiels, B.R., Peleteiro, M.C (2010); Fatal cases of Theileria annulata infection in calves in Portugal associated with neoplastic-like lymphoid cell proliferation. J Vet Sci. 2010.11: 27-34.
5- Razmi, G .R, Barati, F, Aslani, M.R (2009); Prevalence of Theileria annulata in dairy cattle in Mashhad area. Iran. J.Vet. Parasitol. 2009. 23: 81-83.
6-Hassanpour, A., Sabegh, Y. G, Sadeghi-nasab, A., (2013) ; Assessment of serum antioxidant enzymes activity in cattle suffering from Theileriosis. Eur. J. Exp. Biol.2013. 3: 493-96.
7-Woods, K. L., Theiler, R, Mühlemann, M, Segiser A, Huber S, Ansari H R, Pain A, Dobbelaere, D. A. E.,(2013) ; Recruitment of EB1, a Master Regulator of Microtubule dynamics, to the Surface of the Theileria annulata .Schizont. PLoS. Pathog.2013. 9: 1003346.doi:10.1371/journal.ppat.100334.
8-Razavi, S M, Nazifi, S, Bateni, M, Rakhshandehroo, E.,(2011) ; Veterinary Parasitology, 2011, 180, 209-214.
9-Sharma A, R. and Gxutam, O. P.,(1977) ; Tick-borne Diseases and their Vectors. Indian. Journal of Parasitology, 1977. 1, 87-91.
10-Hubbert, W. T., Rryner, J. H., Folby, J. W., Estes, P. C.,(1975) ; Theriogenology, 1975.3, 43-63.
11- Godara, R., Sharma, R.L., Sharma, C.S.,(2009); Bovine tropical theileriosis in a neonate calf. Trop. Anima. Health. Prod. 2009. 42(4):551–553.
12- Fartashvand, M; Nadalian, M.G; Sakha, M; Safi, S.,(2013); Elevated serum cardiac troponin in cattle with Theileriosis. J Vet Intern Med 27: 2013.194-199.
13-Singh SK, Sudan V, Sachan P, Srivastava A.,(2013); Salvage of Theileria infected calves with clinical manifestation of exophthalmia. J .Parasit. Dis. 2013 Doi .10 .1007 /s 12639-013-0364-8.
14- Chandra. K; Syed S. A., Abid Mohd., Sweety R.., Najam A. k.,(2015); "Protection against FCA Induced Oxidative Stress Induced DNA Damage as a Model of Arthritis and In vitro Anti-arthritic Potential of Costus speciosus Rhizome Extract". International Journal of Pharmacognosy and Phytochemical Research .2015. 7 (2): 383–389.
15- Forsyth, L.M., Minns, F.C., Kirvar, E., Adamson, R.E., Hall, F.R., Mcorist, S., Brown, C.G., Preston, P.M.,(1999); Tissue damage in cattle infected with Theileria annulata accompanied by metastasis of cytokine-producing schizont-infected mononuclear phagocytes. J. Comp. Pathol. 1999.120, 39–57.
16-Ahmed, J.S., Glass, E.J., Salih, D.A., Seitzer, U., (2008); Review innate immunity to tropical theileriosis. Innate Immun.j. 2008 (14), 5–12.
17- Shiono, H., Yagi, Y., Chikayama, Y., Miyazaki, S., Nakamura, I.,(2003); The Influence of oxidative bursts of phagocytes on red blood cell oxidation in anemic cattle infected with Theileria sergenti. Free Radic. Res. 2003. 37, 1181–1189.
18-Turrens, J.F., (2004); Oxidative stress and antioxidant defenses: a target for the treatment of diseases caused by parasitic protozoa. Mol. Aspects Med. J.2004. 25, 211–220.
19- Comporti, M., Signorini, C., Buonocore, G., Ciccoli, L.,(2002); Iron release, oxidative stress and erythrocyte ageing. Free Radica. Biol. Med. 2002.32,568–576.
20-Gaal, T., Ribiczeyne-Szabo, P., Stadler, K., Jakus, J., Reiczigel, J., Kover, P., Mezes, M., Sumeghy, L.,(2006); Free radicals, lipid peroxidation and the antioxidant system in the blood of cows and newborn calves around calving. Comp. Biochem. Physiol. B. 2006.143, 391–396.
21-Valko, M., Leibfritz, D., Moncol, J., Cronin, M.T.D., Mazur, M., Telser, J., (2007); Free radicals and antioxidants in normal physiological functions and human disease. Int. J. Biochem. Cell Biol. 2007. 39, 44–84.
22-Harvey, J.W., (2008); The erythrocyte: physiology metabolism and biochemical disorders. In: Kaneko, J.J., Harvey, J.W., Bruss, M.L. (Eds.), Clinical biochemistry of domestic animals, sixth ed. Academic Press, London, 2008.pp. 173–240.
23-Kanias, T., Acker, J.P., (2010); Bio-preservation of red blood cells the struggle with hemoglobin oxidation. FEBS J. 2010. 277, 343–356.
24-Cimen, M. Y.,(2008): free radical metabolism in human erythrocytes. Clin. Chem Acta. J, 2008. 390, 1-11.
25- Dalle-Donne, I., Aldini, G., Carini, M., Colombo, R., Rossi, R., Milzani, A., (2006); Protein carbonization, cellular dysfunction, and disease progression. J. Cell. Mol. Med.2006. 10, 389–406.
26-Coles, E.H.,(1980); Veterinary Clinical Pathology, 3 rd. edition .Saunders Philadelphia .pp. 1980. 75- 90.
27- Taylor, M.A., Coop, R.L., Wall, R.L.,(2007); Veterinary Parasitology. 3rd edth. Blackwell Publishing Ltd, UK. 2007. pp 109-113.
28-Conrad, P.A., Kjemtrup, A.M., Carreno, R.A., Thomford, J., Wainwright, K., Eberhard,M., Quick, R., Telford, S.R., Herwaldt, B.L., (2006) ;Description of Babesia duncanin.sp. (Apicomplexa: babesiidae),from humans and its differentiation from other piroplasms. Int. J. Parasitol. 2006. 36, 779–789.
29-Sambrook J.; Fritsch, E.F. and Maniatis T., (1989); Molecular Cloning: a Laboratory Manual. Cold spring . Harbor Laboratory Press, New York .1989.
30- Weiss, D.J., Wardrop, K .J. Schalm's .,(2010) ; Veterinary Hematology, 6 editions. 2010. (Ames, Wiley-182 Blackwell).
31-Dodge, J.T., Mitchell, C., Hanahan, D.J.,(1963); the preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes. Arch . Biochem. Biophys. 1963. 100, 119–130.
32- Stadtman, E.R., Levine, R. L., (2003) ; Free radical-mediated oxidation of free amino acids and amino acid residues in proteins. Amino. Acids.J. 2003. 25, 207–218.
33-Placer, Z.A., Cushman, L.L., Johnson, B.C.,(1966) ; Estimation of product of Lipid peroxidation (malonyldialdehyde) in biochemical systems. Anal. Biochem.J. 1966.16, 359–364.
34-Wendel, A.,(1980) ; Enzymatic Basis of Detox cation, 1980. Volume.1. pp. 333, Academic. Press, N.Y.
35- Li, Y and Schellhorn, H. E.,(2007) ; Rapid kinetic micro assay for catalase activity. J. Biomol. Tech.2007.18, 185–187.
36-Rezaei, A. S and Dalir-Naghaded, B.,(2006) ; Evaluation of antioxidant status and oxidative stress in cattle infected with Theileria annulata. Veterinary Parasitology, 2006.142, 179-186.
37-Stoltsz, W .H.,(1989) ; Theileriosis in South Africa: A brief review. Rev Sci Tech. 1989.8(1): 93-102.
38-Mishra, A. K., Sharma, N. N., Srivastava, S. C.,(1994);Theileria annulata infection in neonatal bovine calves. Acta. Vet. Hung.1994. 42 (1) 99-102.
39- Issi, M and Gul, Y.,(2008) ; Tropical theileriosis in newborn two calves. Yüzüncü yıl Üniversitesi .Veterinary .Fakültesi . Dergisi.2008. 19 (2) 67-69.
40-Sudan V; Sharma, R. L; Borah, M. K; Mishra, R.,(2012); Acute bilateral proptosis in a cross bred calf naturally infected with Theileria annulata .J. Parasite. Dis (July-Dec 2012) 36(2):215–219.
41-Onoe, S.,Sugimoto, C.,Tanaka, M.,Kubota, S., Hirai, T.,Yonemichi, H.,Mori, K ., Onuma, M.,(1994) ; Prenatal infection with Therleria sergenti in calves . J. Protozool . Res.1994. 4 (3) 119-123.
42-Saville, W.J.A.,(2002) ; cerebral theileriosis. In: Smith BP (Eds.).Large animal internal medicine. 3rd ed. St. Louis, USA: Mosby; 2002.917 -918.
43-Dabak, M; Aktas, M and Dabak, D. O.,(2004) ; Cerebral theileriosis in a Holstein calf. Vet Rec.J.2004; 154(17): 533-534.
44-Urquhart, G. M, Armour, J; Duncan, J.L; Dunn, A. M, Jennings, F.W.,(2003) ; Veterinary parasitology. Blackwell Science Ltd., UK, 2003. pp 246–249.
45-Soulsby, E. J.L.,(2005) ; Helminths, arthropods and protozoa of domesticated animals, ELBS-7. Bailliere Tindal, London, 2005. pp 728–737.
46- Lefevre, P.S; Blancou, J; Chermette, R; Uilenberg, G.,(2010) ; Infectious and parasitic diseases of livestock. Lavoisier Tec & Doc.2010.,pp 1839–1866.
47-Mohammad,T. K ., Javad, A. H, Ezzat, O.F.,(2014) ; Occurrence of congenital cerebral theileriosis in a newborn twin Holstein calves in Iran: Case report. V.R. Forum. 5 (3) 2014. 237 – 241.
48-Khan, I.A., Khan, A., Hussain, A., Riaz, A., Aziz, A.,(2011) ; Hemato-Biochemical Alterations in Cross Bred Cattle Affected with Bovine Theileriosis in Semi-Arid Zone. Pak .Vet .J. 2011.31(2): 137-140.
49-Singh A., Singh, J., Grewal, A S., Brar, R S.,(2001); Studies on some blood parameters of cross bred calves with experimental Theileria annulata infections. Vet. Res. Comm. 2001. 25, 289–300.
50-Omuse, J. K.,(1987); A comparative hematological picture of field cases of East coast fever, Anaplasmosis and Babesiosis in bovine around Kabete. In: "Tick born disease and their vector"1st ed by Wild J.K, Center for tropical veterinary medicine. University of Edinburgh. 1987. PP: 181-187.
51- Morrison, W. I.,(2004) ; Theileria annulata: Kinetics of infection in lymphoid system of cattle. Exper. Parasitol. 2004. 52(2): 248-260.
52-Gitto, E.,Pellergrino, S.,Gitto, P.,Barber, I.,Reiter, R.,(2009) ;Oxidative stress of the newborn in the pre- and postnatal period and the clinical utility of melatonin. J. Pineal .Res.46, pp. 2009.128-139.
53-Grewal, A., Ahuja, C.S., Singha, S.P.S., Chaudhary, K.C.,(2005); Status of lipid Peroxidation, some antioxidant enzymes and erythrocyte fragility of crossbred cattle naturally infected with Theileria annulata. Vet. Res. Commun . 2005.29, 387–394.
54-McMillan, D.C., Powell, C.L., Bowman, Z.S., Morrow, J.D., Jollow, D. J.,(2005) ; Lipids versus proteins as major targets of pro-oxidant, direct-acting hemolytic agents. Toxicol . Sci.J.2005. 88, 274–283
55-Yagi, Y., Thongnoon, P., Shiono, H., Chikayama, Y.,(2002) ; Increase in oxidized proteins in Theileria sergenti infected erythrocyte membrane. J. Vet. Med. Sci. 2002. 64, 623–625.
Published
2019-02-04
How to Cite
osman, P. D. A. (2019). Occurrence of congenital tropical theileriosis associated with oxidative stress and antioxidant response in crossbreed newborn calves in New Valley Governor ate. Egypt. EPH - International Journal of Agriculture and Environmental Research (ISSN: 2208-2158), 5(1), 01-18. Retrieved from https://ephjournal.com/index.php/aer/article/view/1024