Vol 5 No 8 (2019): EPH - International Journal of Medical and Health Science (ISSN: 2456 - 6063)
Articles

A REVIEW ARTICLE THE ROLE OF DENDRITIC CELLS IN THE CONTROL OF INNATE IMMUNITY

James D Yelima
Academic
Dr Silas Anayo Ufelle
Bio
Dr Audu Abdullahi Bukar
Bio
Dr Dauda Madubu Milgwe
Bio
Oyeleke Kikilemo Olayemi
Bio
Chidozie Kenechi Chikwendu
Bio
Published August 28, 2019
Keywords
  • innate inflammatory responses,
  • T cells and B cells,
  • adaptive immune response,
  • innate immunity
How to Cite
Yelima, J. D., Ufelle, S. A., Bukar, A., Milgwe, D. M., Olayemi, O. kikilemo, & Chikwendu, C. K. (2019). A REVIEW ARTICLE THE ROLE OF DENDRITIC CELLS IN THE CONTROL OF INNATE IMMUNITY. EPH - International Journal of Medical and Health Science (ISSN: 2456 - 6063), 5(8), 18-25. Retrieved from https://ephjournal.com/index.php/mhs/article/view/1426

Abstract

Abstract: Dendritic cells play an important role in host immunity by inducing innate inflammatory responses to pathogens, efficiently priming immature T cells, activating memory T cells and promoting B cell activation. Dendritic cells are also integral in maintaining steady- state immune homeostasis by continually presenting tissue-derived self-antigens to CD4+ and CD8+ T cells in the absence of inflammatory signals, leading to tolerance against those self-antigens. The important of innate immunity lies not only in directly confronting pathogenic and non-pathogenic insults but also in instructing the development of an efficient adaptive immune response.

 

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