Vol 5 No 10 (2019): EPH - International Journal of Medical and Health Science (ISSN: 2456 - 6063)

Maternal deaths related to severe preeclampsia at the University Hospital of Gynecology and Obstetrics Befelatanana: Risk factors

T Razafindrainibe
Réanimation adulte, CHU-GOB
S Rakotonomenjanahar
Service d’anesthésiologie, CHU-JDR
NMP Rahanitriniaina
Service de Réanimation Chirurgicale, CHU-JRA
JG Raelison
Service d’Anesthésiologie, CHU d’Antsiranana
M Andrianirina
Réanimation adulte, CHU-GOB
NE Raveloson
Published October 19, 2019
  • Deaths,
  • factors,
  • mortality,
  • severe preeclampsia
How to Cite
T Razafindrainibe, S Rakotonomenjanahar, NMP Rahanitriniaina, JG Raelison, M Andrianirina, & NE Raveloson. (2019). Maternal deaths related to severe preeclampsia at the University Hospital of Gynecology and Obstetrics Befelatanana: Risk factors. EPH - International Journal of Medical and Health Science (ISSN: 2456 - 6063), 5(10), 14-24. Retrieved from https://ephjournal.com/index.php/mhs/article/view/1569


Introduction: Severe preeclampsia is a pathology of pregnancy that is the second leading cause of maternal mortality in the world. Thus, this study aim is to determine the factors related to this high mortality to improve the management.

Method: Case-control study of the records of mothers admitted to the Gynecological and Obstetric Hospital of Befelatanana for severe pre-eclampsia from January 2013 to December 2014. The cases being the deceased and the witnesses the survivors.

Results: We collected 160 files that met the inclusion criteria, including 32 cases with a mean age of 27.5 ± 12.5 years and 128 controls with an average age of 29 ± 14 years. We were able to draw 19 clinical, paraclinical, and therapeutic factors incriminated in death from PES. Thus, women living in urban, low-level education, multigeste, multiparous, having toxic habits and having done little or no monitoring of pregnancy are the most likely to die. The presence of clinical (cardiovascular, pulmonary and renal) and paraclinical abnormalities is a mortality factor. The most at risk of death among all complications are eclampsia, acute renal failure, and HELLP syndrome. Emergency cesarean delivery would reduce the risk of death; however, the choice of anesthesia would hinder the benefits of this gesture.

Conclusion: Prevention by good monitoring of pregnancy by qualified people and referral in specialized gynecological centers are the basis of the management of PES to avoid the appearance of complications and reduce the mortality rate by PES.


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